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. CRK12:CYC9 interact in a yeast two-hybrid assay and form an Lively protein kinase elaborate in procyclic and bloodstream form T. brucei, et al CDK12 inhibition reverses de novo and purchased PARP inhibitor resistance in BRCA wild-form and mutated products of triple-negative breast cancerBlocking the conserved ATP binding web-site is the most typi